Brain metastases (BM) are rarely reported in patients with neuroendocrine carcinoma (NEC) of non-lung origin and neuroendocrine tumors (NET) of the gastroenteropancreatic (GEP) or bronchopulmonary system. Prevented from simply buying a Disney comic book by his parents, Krϋger would study and memorise images of the character, then quickly run home to draw it, going back to the shop if he b… Context Pancreatic ductal adenocarcinoma is a dismal disease with one of the worst prognoses amongst solid tumors. The optimal treatment sequence... Background: Halle Reports. Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. Gemcitabine is the standard chemotherapy for patients with metastatic pancreatic adenocarcinoma (MPA). All Titles Year Calendar Place Author. However, predictive markers for patient selection are still missing. His faces are benevolent but subversive tribute to the world of the beautiful surface, the rock and pop culture of the sixties, with which the artist has cultivated an almost ritual relationship. Marita Koch Meier (Wismar, 18 febbraio 1957) è un'ex velocista tedesco orientale, campionessa olimpica dei 400 metri piani a Mosca 1980.. Durante la propria carriera ha raccolto un notevole numero di record mondiali: 16 all'aperto, così come 14 negli eventi indoor; è … Recently, it has been shown that plasma levels of CgA correlate with tumor load and predict survival of patients with NEN of the small bowel. In addition, SSA exert significant anti-proliferative effects in mid-gut and pancreatic NET (PanNET). SOLD LISTINGS FOR Sebastian Kruger "Good Clint Eastwood 28x45" Limited Edition Print: From the Edition of 99 I have one and want to sell it SOLD "Jagger" Limited Edition Print: Giclee I have one and want to sell it SOLD "Jimi Hendrix Ap 2006" Limited Edition Print: Giclee on Canvas I … Per definition, both tumor parts account for at le... Pancreatic neuroendocrine tumors (PNETs) represent a heterogeneous group of neuroendocrine neoplasms with varying biological behaviour and response to treatment. Molecular pathways that determine the malignant phenotype are still insufficiently understood and have limited the use of effective combinat... Background Many sporadic non-functioning pNET patients are already metastatic at the time of diagnosis, and the therapeutic approach to such patients is mostly palliative. Randomized clinical trials evaluating intensified chemotherapies including FOLFIRINOX and nab-paclitaxel plus gemcitabine (NAB+GEM) have shown improvement in sur... Pancreatic neuroendocrine tumours (pNETs) represent rare neoplasms of all NETs often presenting without functional activity. In seguito, ha sviluppato un personalissimo stile nelle caricature di personaggi famosi, rientrando nella corrente artistica definita “New Pop Realism”. Wir würden uns deshalb sehr über Ihre Teilnahme freuen. Historical Books Directories. Join Facebook to connect with Sebastian Krug and others you may know. Studierenden-Service-Center. Only verified researchers can join ResearchGate and send messages to other members. wir, das Universitätsklinikum Halle (Saale), führen im Moment eine Umfrage über die Nutzung unserer Internetseite durch. Sebastian Krug Retail Director Australia at CHEP - Brambles Ltd. at CHEP Australia Köln und Umgebung, Deutschland 500+ Kontakte Study Guide; Paths to University. Esophageal cancer represents a heterogeneous malignancy mostly diagnosed in advanced stages. View the profiles of people named Sebastian Krug. makes no a priori assumptions regarding the number of spots or their Cytotoxic chemotherapy, along with alkylating agents and antimetabolites as well as mole... e15774 Impact of intensified chemotherapy in metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical routine: A Pan-European study. Its ability to develop chemoresistance mechanisms towards cytotoxic drugs is the main cause of treatment failure. These tumors are characterized by clinical and prognostical heterogeneity and are predominantly diagnosed in a metastatic stage. Sebastian Krug & Matthias Lengnick & Hans-Werner Wohltmann, 2014. " The basic database underlying this analysis is available as S1. Keywords Places Authors Years 8 Results. Jens Werner (München), Sebastian Krug (Halle/ Saale) 08:30–08:38 C-reactive protein (CRP) is associated with poor prognosis by promoting growth signaling pathway activation in pancreatic neuroendocrine neoplasms K8 main sequence star known to exhibit large cool spots on its surface. However, symptomatic brain metastases are associated with dismal prognosis, so early detection and treatment could be advisable. Sehen Sie sich das Profil von Sebastian Krug auf LinkedIn an, dem weltweit größten beruflichen Netzwerk. Sebastian Ströbel, attore tedesco (Karlsruhe, n.1977) Wolfgang Stumph, attore e cabarettista tedesco (Wünschelburg, n.1946) Florian Stetter, attore cinematografico tedesco (Monaco di Baviera, n.1977) Hans Stüwe, attore cinematografico, regista teatrale e musicologo tedesco (Halle, n.1901 - Berlino, †1976) To identify kinases whose inhibition acts synergistically with erlotinib, we employed a kinome-wid... Das Adenokarzinom des Pankreas bietet je nach Lokalisation und Ausbreitung ein unterschiedliches klinisches Beschwerdebild. Pdcd4 levels are reduced in various tumours and during malignant transformation. Streptozocin (STZ) based chemotherapy is recommended for patients with metastatic pancreatic neuroendocrine tumors (pNET). University students and faculty, institute members, and independent researchers, Technology or product developers, R&D specialists, and government or NGO employees in scientific roles, Health care professionals, including clinical researchers, Journalists, citizen scientists, or anyone interested in reading and discovering research. A known cystic lesion of the liver which had been followed for years by ultrasound examinations and was regarded as a bland hepatic cyst was identified as a metastasis of a neuroendocrine neop... Pancreatic ductal adenocarcinoma is a stroma-rich and highly challenging cancer to treat. The young solar analog LO Pegasi is a rapidly rotating (P ≈ 10.2 hr) We present surface maps based on BVRI photometry obtained at Perkins Historical Maps. Due to our privacy policy, only current members can send messages to people on ResearchGate. Observatory from May-July 2011 and inverted with an algorithm which Pancreatic ductal adenocarcinoma (PDAC) is characterised by an extremely poor overall survival (OS) compared to other solid tumours. Admission requirements Over recent years, it has become increasingly evident that the complex network of soluble cytokines, growth factors, proteases, and components of the extracellular matrix collaboratively interact within the tumor microenvironment, sustaining and driving cancer... Pancreatic cancer is characterized by a high degree of resistance to chemotherapy. Das Beantworten der Fragen dauert auch nur wenige Minuten. Background Sebastian KRUG, Medical Doctor of Martin Luther University Halle-Wittenberg, Halle (Saale) (MLU) | Read 80 publications | Contact Sebastian KRUG In a survey, we investigated the influence of COVID-19 on the care of NET patients in the German speaking countries Germany, Austria and Switzerland. Uber pradiktive und prognostische Marker in dieser Patientengruppe ist bislang wenig bekannt. To identify risk genes for alcoholic CP and to evaluate their relevance in non-alcoholic CP, we pe... Background: Patienten und Methoden: 79 Patie... Ein 79-jähriger Patient wurde mit Gewichtsverlust, subfebrilen Temperaturen und unklaren Beschwerden beim Kauen eingewiesen. © 2008-2020 ResearchGate GmbH. Sebastian Krϋger was born in Hamlin, Germany on 30th June 1963. His interest in illustration began early, at the age of three, when he became obsessed with drawing the character of Donald Duck as he had seen in Disney movies and cartoons. However, symptomatic brain metastases are associated with dismal prognosis, so early detection and treatment could be advisable. Objective: The COVID-19 pandemic challenges health care systems worldwide. Sebastian Krug, Martin-Luther Universität Halle/Wittenberg, Germany Arutha Kulasinghe, Queensland University of Technology, Australia Dhruv Kumar, Amity Institute of Molecular Medicine & Stem Cell Research, Amity University Noida, India Rahul Kumer, Iriving Medical Center, Columbia University, USA Sebastian Günther è su Facebook. A nationwide survey, Eine abszessverdächtige Raumforderung in der extraokulären AugenmuskulaturSuspected abscess formation in the inferior rectus muscle, Correction: Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells, Brain metastases in patients with neuroendocrine neoplasms: Risk factors and outcome, The nasogastric tube is stuck - and causes coughing and dyspnoea: A rare complication, Charakterisierung von epigenetischen Modulatoren in pankreatischen Neuroendokrinen Neoplasien, DEGUM-CEUS-HCC-Studie zur Kontrastmittelsonografie in der nicht-invasiven Diagnostik des hepatozellulären Karzinoms bei Risikopatienten – eine prospektive, multizentrische Studie, Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells. Katharina Theuerkorn's 8 research works with 8 citations and 288 reads, including: Correction: Interaction between somatostatin analogues and targeted therapies in neuroendocrine tumor cells Sebastian has 1 job listed on their profile. Color-coded dupl... Pancreatic ductal adenocarcinomas belong to the most aggressive solid malignancies. In addition, dacarbazine (DTIC) was described as an alternative alkylating therapy option for PNETs. Case presentation Although targeted therapies have been shown to improve the survival for patients at advanced stage, resistance to current therapies frequently occurs during the course of therapy. Sebastian Krug is an actor, known for Kümo Henriette (1979). In recent years, FOLFIRINOX and Nab-paclitaxel (NAB) + GEM regimens have shown significant survival benefits compared to gemcitabine in clinical trial settings. Sebastian Krug Personaloberarzt Schwerpunkte: Gastrointestinale Tumore, Neuroendokrine Tumore Telefon: 0345/ 557-2665 Fax: 0345/ 557-2253: Frank Noack Schwerpunkte: Pneumologie / Notfallmedizin Telefon: 0345/ 557-2018 Fax: 0345/ 557-5822 : apl. As the incidence of the disease is rising and the treatment options are limited, PDAC is projected to be the 2nd leading cause of cancer-related deaths in the United States by 2030. Ziel: Charakterisierung von klinisch-pathologischen Patien... Ein 59-jähriger Patient wurde mit rezidivierender Flush-Symptomatik und pathologisch erhöhter 5-Hydroxyindolessigsäure im Sammelurin eingewiesen. They combine a neuroendocrine component, usually a poorly differentiated neuroendocrine carcinoma, with a nonneuroendocrine part consisting mostly of an adenocarcinoma component. In parallel, molecularly targeted therapies (MTT) have been shown to improve progr... 4103 Authors. Sehen Sie sich auf LinkedIn das vollständige Profil an. Historical Books Directories. Worldwide, squamous cell carcinomas (SCCs) continue to be the most prevalent subtype; however, in the Western countries, the incidence of adenocarcinomas is increasing and will exceed that of SCC in the near future. Methods: It is assumed that this is as well valid for NEN of th... Hindgut-NEN-data set. Furthermore, high amounts of Pdcd4 showed the potential to repress malignant transformation. So far, the effects of Pdcd4 seemed to be cell type specific. Objective Weiterführende Informationen erhalten Sie in der, Schwerpunkte: Gastrointestinale Tumore, Neuroendokrine Tumore, Schwerpunkte: Pneumologie / Notfallmedizin, Schwerpunkte: Hepatologie / Lebertransplantation, Schwerpunkte: Pankreatologie, Leiter Endoskopie, Schwerpunkte: Chronisch-Entzündliche Darmerkrankungen, Lehrbeauftragter, Schwerpunkte: Pneumologie / Cystische Fibrose, Schwerpunkte: Hepatologie, Interventionelle Hepatologie (TIPS), Funktionsabteilungen und klinisch-diagnostische Labore, Förderverein des Universitätsklinikums Halle (Saale). Alcohol-related pancreatitis is associated with a disproportionately large number of hospitalisations among GI disorders. In this situation, guidelines for health care professionals in endoscopy units with increased risk of infection from inhalation of airborne droplets, conjunctival contact and faeces are urgently needed. Unsere Datenschutzinformationen finden Sie unter, Diese Seite benutzt Cookies, um seinen Besuchern das beste Webseiten-Erlebnis zu ermöglichen. We present an individual case of paraneoplastic GH- and IGF-1 secretion in a patient with pulmonary NET. Dabei können eine adäquate Anamneseerhebung und eine gezielte körperliche Untersuchung erste Hinweise für ein fortgeschrittenes Tumorleiden ergeben. In this situation, guidelines for health care professionals in endoscopy units with increased risk of infection from inhalation of airborne droplets, conjunctival contact and faeces are urgently needed. Organizzazione insieme a Sebastian Luft (Marquette University, USA) A phase II, open label, multicenter trial of avelumab in patients with advanced, metastatic high-grade neuroendocrine carcinomas NEC G3 (WHO 2010) progressive after first-line chemotherapy (AVENEC). Patient data for statistical analyses. Sebastian Krug, Actor: Kümo Henriette. Brain metastases (BM) are rarely reported in patients with neuroendocrine carcinoma (NEC) of non-lung origin and neuroendocrine tumors (NET) of the gastroenteropancreatic (GEP) or bronchopulmonary system. Considering its biological action conflicting data in the literature exist and, consequently, our own studies point to a cell type specific action of Pdcd4. During the last decade, seve... Introduction: 23.5k Followers, 50 Following, 1,221 Posts - See Instagram photos and videos from Sebastian Krüger (@sebastiankrugerofficial) However, data about biomarkers involved in the 5-FU metabolism to predict response are still limited. Paraneoplastic neurological syndromes (PNS) have frequently been described in patients with lung or breast cancer. Halle Reports. Martin Jung, Ajay Sharma, Dariush Hinderberger, Sebastian Braun, Ulrich Schatzschneider, Eva Rentschler Long-distance magnetic interaction of exchange-coupled copper dimers with nitronyl nitroxide and tert-butyl nitroxide radicals Inorg. Meth... For critically ill patients, it is very important that enteral nutrition is established as early as possible. Infiltrating myeloid cells have been identified not only in invasive tumors, but also in early pre-invasive pancreatic intraepithelial precursor lesio... Background and aim: Study. Solid pseudopapillary neoplasms of the pancreas (SPNs, Gruber-Frantz-Tumor) are a rare entity representing 1-5% of all exocrine pancreatic tumors. Chemotherapy with 5-FU and Streptozotocin (STZ) is recommended as first-line treatment in patients with metastatic pancreatic neuroendocrine neoplasms (PNEN).